منابع مشابه
One-year Investigator-blind Randomized Multicenter Trial Comparing Asacol 2.4 g Once Daily with 800 mg Three Times Daily for Maintenance of Remission in Ulcerative Colitis
BACKGROUND Mesalazine (Asacol) is still widely prescribed in divided doses for ulcerative colitis (UC), despite evidence that adherence is improved by once-daily (OD) prescribing. We aimed to investigate whether OD Asacol was as effective as three times (TDS) daily dosing, and to evaluate the role of treatment adherence. METHODS An investigator-blind randomized trial was undertaken comparing ...
متن کاملOnce-daily aminoglycoside administration.
Once-daily aminoglycoside dosing is effective in treating gram-negative infections, including those associated with bones and joints.
متن کاملOnce-daily dosing of gentamicin.
Gentamicin remains one of the most effective and commonly used antimicrobials in the armamentarium of clinicians treating pelvic infections. It continues to reliably cover the aerobic gram-negative rods seen within polymicrobial infections. Available in its generic form, it becomes the low-cost drug of choice in these settings. So why mess with success? As Wiesenfield et al point out in this is...
متن کاملOnce-daily metoprolol for hypertension.
Introduction One of the problems encountered in the treatment of hypertension is that the long duration of therapy coupled with multiple dosage regimens in asymptomatic patients lead to poor compliance (Sackett and Haynes, 1976). Once-daily treatment regimens with P-adrenoceptor blockers other than metoprolol have been shown to be effective (Wilcox, 1978; Watson, Stallard and Littler, 1980). It...
متن کاملOnce-Weekly Exenatide Versus Once- or Twice-Daily Insulin Detemir
OBJECTIVE This multicenter, open-label, parallel-arm study compared the efficacy and safety of exenatide once weekly (EQW) with titrated insulin detemir in patients with type 2 diabetes inadequately controlled with metformin (with or without sulfonylureas). RESEARCH DESIGN AND METHODS Patients were randomized to EQW (2 mg) or detemir (once or twice daily, titrated to achieve fasting plasma gl...
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ژورنال
عنوان ژورنال: Gut
سال: 2011
ISSN: 0017-5749
DOI: 10.1136/gut.2011.239301.74